Chloroform
Chloroform
HS Code : 29031300 | CAS NO. : 67-66-3
Basic Information:
- Chemical Name: Chloroform
- Formula: CHCl₃
- Molecular Weight: 119.38 g/mol
- Appearance: Clear, colorless liquid
- Odour: Sweet, characteristic odour
- Taste: Not Applicable
- Solubility: Slightly soluble in water, miscible with organic solvents
Packing Details: • 500 ml Amber glass bottle • 2.5 Ltr Amber glass bottle • 25 kg HDPE Drum •50 Kg HDPE Drum • 200 Ltr HDPE Drum
Storage & Handling
- Store in a cool, dry and well-ventilated area
- Keep containers tightly closed and in light-resistant containers
- Protect from heat, sunlight and air exposure (to prevent decomposition)
- Store away from strong bases, oxidizing agents and metals
- Ensure adequate ventilation during handling.
Safety
- Harmful if inhaled, ingested or absorbed through skin
- May cause dizziness, liver and kidney damage
- Suspected carcinogenic effects on prolonged exposure
- Avoid inhalation of vapors
- Use gloves, mask and safety goggles.
- UN1888/Class 6.1
Industry Wise Application
Industrial Chemical Manufacturing
- Refrigerant Production:The most prominent use is as a precursor in the production of Chlorodifluoromethane (HCFC-22 or Freon 22), a refrigerant used in air conditioners and large-scale freezers.
- Fluoropolymer Production:It is utilized as an intermediate in manufacturing polytetrafluoroethylene (PTFE), commonly known as Teflon, and other fluorinated plastics.
- Pharmaceutical Synthesis:Used as a raw material or solvent in the production of various drugs, antibiotics, vitamins, and flavors.
- Pesticide Formulations:Acts as a reagent and solvent in the production of agricultural chemicals, including fumigants like chloropicrin
Solvent Applications
- Industrial Solvent:Because it dissolves a wide range of organic compounds, it is used to extract oils, fats, grease, rubber, wax, resins, and alkaloids.
- Dry Cleaning & Cleaning Agents:Formerly used in laundries as a spot remover and in industries for degreasing machinery.
- Manufacturing Processes:Used in the preparation of adhesives, floor polishes, and artificial silk.
Laboratory & Scientific Applications
- Laboratory Solvent:A common solvent used in analytical chemistry and organic synthesis.
- DNA/RNA Isolation:Mixed with phenol in molecular biology for separating nucleic acids during extraction.
- Spectroscopy:Pure chloroform is used as a solvent in Fourier Transform Infrared Spectroscopy (FTIR) and NMR analysis (as deuterated chloroform – CDCL3)
- Preservation:Used for preserving biological specimens in histology and analytical chemistry.
Medical Applications
- Anaesthesia:Historically, it was extensively used as an inhalation anaesthetic in surgeries (often mixed with ether).
- Dentistry:Occasionally used in dentistry for dissolving gutta-percha during root canal treatments.
- Note: These uses have been largely discontinued due to severe toxicity and carcinogenicity
Other Uses
- Industrial Intermediate:Used to synthesize dyes and in the rubber industry.
- Indirect Food Additive:Included in some food packaging materials as an adhesive component.
- Entomology:Historically used as a killing agent in insect collecting
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